GSTM1 Antikörper (C-Term)

Produktnummer ABIN374509

Dieser Ziege Polyklonal Antikörper erkennt spezifisch GSTM1 in WB. Er zeigt eine Reaktivität gegenüber Human und Affe.

Kurzübersicht für GSTM1 Antikörper (C-Term) (ABIN374509)

Target: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Reaktivität: Human, Affe

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser GSTM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GSTM1 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to GSTM1 and will also recognise GSTM2 protein.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence CVFSKMAVWGNK, from the C Terminus of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/1000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GSTM1

Target: GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))

Andere Bezeichnung: GSTM1

Hintergrund: Glutathione S transferases are encoded by two distinct supergene families and a total of eight distinct classes of the soluble cytoplasmic mammalian glutathione S transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. The mu class of these enzymes, to which GSTM1 and 2 belong, functions in the detoxification of electrophilic compounds by conjugation with glutathione. The genes encoding the mu class of enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs and null mutations of this gene have been linked with an increase in a number of cancers.Synonyms: GST class-mu 1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, Glutathione S-transferase Mu 1

Gen-ID: 2944, 9606

UniProt: P09488

Pathways: Negative Regulation of Transporter Activity